David A. Sinclair, PhD, is a professor in the Department of Genetics at Harvard Medical School and co-director of the Paul F. Glenn Center for the Biological Mechanisms of Aging.
Dr. Sinclair’s work focuses on understanding the mechanisms that drive human aging and identifying ways to slow or reverse aging’s effects. In particular, he has examined the role of sirtuins in disease and aging, with special emphasis on how sirtuin activity is modulated by compounds produced by the body as well as those consumed in the diet, such as resveratrol. His work has implications for human metabolism, mitochondrial and neurological health, and cancer.
▶︎ Get the episode’s show notes, timeline, and transcript.
▶︎ Detailed overview of NAD+
▶︎ Detailed overview of nicotinamide riboside
▶︎ Detailed topic page on nicotinamide mononucleotide
▶︎ Follow Dr. David Sinclair on .
▶︎ BOOK: Lifespan: Why We Age and Why We Don’t Have To
▶︎ Visit the Sinclair Lab
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▶︎ Submit your raw genetic data. You can find the Sirtuin SNP report at:
